Clinical Physiology: Grants

Current projects, most recent first
2025 - 2028	Rittner, Krug, Schindehütte	Project 7 "Comparison of human and rodent neuronal barriers in pain resolution and their manipulation", in: DFG Klinische Forschungsgruppe (KFO 5001/2), coordinators C. Sommer and H. Rittner (Würzburg) "Peripheral mechanisms of pain and their resolution"
2023 - 2026	Piontek	DFG Research Grant (PI 837/4-3) "Molekulare Architektur Claudin-basierender Tight Junction-Stränge und parazellulärer Ionenkanäle"
2022 - 2026	Krug, Schulzke	Project B06 "Interplay of the impaired tight junction and the subjacent immune cells in IBD", in: DFG Transregio Collaborative Research Center (TRR 241/2), coordinators C. Becker (Erlangen) and B. Siegmund (Berlin) "Immune-epithelial communication in inflammatory bowel diseases"
2022 - 2026	Schulzke	Coordinator, (deputy coordinator Dorothee Günzel, scientific coordinator Rita Rosenthal) DFG Research Training Group (GRK 2318/2) "Tight junctions and their proteins: molecular features and actions in health and disease (TJ-Train)", Summary
2022- 2026	Günzel, Scheffel	therein: Project A1, "Impedance spectroscopy of epithelial barrier properties"
2022 - 2026	Piontek, Roderer	therein: Project A2, "Structure-based modification of Clostridium perfringens enterotoxin to target claudins"
2022 - 2026	Fromm, Piontek	therein: Project A3, "Claudin- and TAMP-mediated water transport"
2022 - 2026	Schulzke, Bücker	therein: Project C1, "Toxin effects on paracellular intestinal barrier function"
2022 - 2026	Krug	therein: Project C2, "Role of the tricellular tight junction in inflammatory bowel diseases (IBD)"
2021 - 2024	Schulzke	DFG Research Grant (Schu 559/11-5) "Mechanismen epithelialer Barrierestörung bei gastrointestinalen Infektionen"
2021 - 2024	Günzel	DFG Research Grant (GU 447/14-2) "Functional interaction of claudins in renal ion transport"
Finished projects, since 2009
2021 - 2024	Rittner, Krug	Project 7 "Neuropathic pain resolution by nerve barrier sealing via endogenous netrin-1", in: DFG Klinische Forschungsgruppe (KFO 5001/1), coordinators C. Sommer and H. Rittner (Würzburg) "Peripheral mechanisms of pain and their resolution"
2021 - 2023	Piontek	DFG Research Grant (PI 837/4-2) "Molekulare Architektur Claudin-basierender Tight Junction-Stränge und parazellulärer Ionenkanäle"
2017 - 2020 2020 - 2022	Bücker, Schulzke	Project IP8 "Strengthening the intestinal barrier in Campylobacter infection" and Project Z4 "In vitro assays", in BMBF Consortium "Preventing and combating Campylobacter infections: On track towards a One Health approach (PAC-CAMPY)“, Coordinator Thomas Alter, VetMed FU Berlin
2020	Günzel et al.	DFG major instrumentation (Großgerät, 700 T€) STED super-resolution confocal microscope
2018 - 2022	Krug, Schulzke	Project B06 "Interplay of the impaired tight junction and the subjacent immune cells in IBD", in: DFG Transregio Collaborative Research Center (TRR 241/1), coordinators C. Becker (Erlangen) and B. Siegmund (Berlin) "Immune-epithelial communication in inflammatory bowel diseases"
2018 - 2021	Krug, Rittner	DFG Research Grant (KR 3807/7-1) "Neuropathic pain resolution by nerve barrier sealing and netrin-1", together with Heike Rittner, Würzburg (RI 817/12-1)
2017	Bachmann (Anatomie)	DFG major instrumentation (Großgerät) Field emission scanning electron microscope (FESEM). In the user group: Fromm, Krug, Piontek "Paracellular versus transcytotic macromolecule passage / Organization of claudins in nanodomains"
2017 - 2022	Schulzke	Coordinator, (deputy coordinator Günzel) DFG Research Training Group (GRK 2318/1) "Tight junctions and their proteins: molecular features and actions in health and disease (TJ-Train)", Summary
2017 - 2022	Günzel	therein: Project A1, "Impedance spectroscopy of epithelial barrier properties"
2017 - 2022	Piontek, Krause	therein: Project A2, "Structure-based modification of Clostridium perfringens enterotoxin to target claudins"
2017 - 2022	Fromm, Schulzke	therein: Project A3, "Claudin- and TAMP-mediated water transport"
2017 - 2022	Schulzke, Troeger	therein: Project C1, "Toxin effects on paracellular intestinal barrier function"
2017 - 2022	Krug, Fromm	therein: Project C2, "Role of the tricellular tight junction in inflammatory bowel diseases (IBD)"
2015 - 2019	Aebischer, Schulzke	Project B3 "Giardia duodenalis – Dendritic cell interaction and intestinal barrier function", in: DFG Research Training Group (GRK 2046/1) Coordinator S. Hartmann: "Parasite infections: From experimental models to natural systems". Continued 2019 - 2024, however, due to changed DFG rules the Co-PIs (here: Schulzke) are no longer part of the grant
2015 - 2018	Piontek, Krause	DFG Resarch Grant (PI-837/4-1) "Molecular architecture of claudin-based tight junction strands and paracellular ion channels"
2014 - 2018	Fromm	DFG Research Grant (FR 652/12-1) "Tight junction protein-mediated water transport"
2014 - 2016	Schulzke	DFG Research Grant (Schu 559/11-2) "Mechanismen epithelialer Barrierestörung bei gastrointestinalen Infektionen"
2016	Schulzke	International Conference "Tight junctions and their proteins", Berlin, 08.09.16 - 10.09.16 (Schu 559/13-1)
2014	Schulzke, Siegmund	DFG Major Research Instrumentation (INST 335/515-1) Confocal laser-scanning microscope
2010 - 2013 2014	Fromm, Schulzke Günzel, Schulzke	Project B2 "Paracellular intestinal barrier - effects of probiotics and feed additives", in: DFG Collaborative Research Center 852 (SFB 852/1), Coordinator J. Zentek: "Nutrition and intestinal microbiota - host interaction in the pig"
2010 - 2012	Fromm	Coordinator: DFG Research Unit 721 (FOR 721/2) "Molecular structure and function of the tight junction"
2010 - 2012	Fromm, Amasheh	Project 1 "Characterization of tight junction proteins as barrier or channel formers", in: DFG Research Unit 721 (FOR 721/2) "Molecular structure and function of the tight junction"
2010 - 2012	Günzel	Project 7 "Renal claudins and their interactions", in: DFG Research Unit 721 (FOR 721/2) "Molecular structure and function of the tight junction"
2010 - 2012	Rittner, Brack, Fromm	Project 8 "Tight junction proteins as permeability regulators of the perineurium and of the antinociception perineurallly applied drugs", in: DFG Research Unit 721 (FOR 721/2) "Molecular structure and function of the tight junction"
2010 - 2012	Fromm, Schulzke, Krug	Project Z "Freeze fracture electron microscopy" und two-path impedance spectroscopy, in: DFG Research Unit 721 (FOR 721/2) "Molecular structure and function of the tight junction"
2009 - 2012	Aust, Amasheh, Fromm	DFG Research Grant (AU 132/7-1 and AM 141/4-1) "Meaning of CD97 in experimental colitis and ulcerative colitis: functional characterization of the molecule in intestinal epithelial cells"
2011 - 2012	Amasheh	DFG Grant (AM 141/5-1), program Initiation and enhancement of bilateral cooperation. Joint project and mutual research stays of Prof. A. Markov, St. Peterburg, Russia, in Berlin and of S. Amasheh in St. Petersburg
2011 - 2012	Fromm, Krug	DFG Grant (FR 852/11-1), program Initiation and enhancement of bilateral cooperation. Joint project and research stays in Berlin of Dmitry Stepanov, St. Peterburg, Russia
2011 - 2012	Krug	DFG Grant (KR 3807/1-1) program Initiation and enhancement of bilateral cooperation. Joint project and research stay with Prof. Jerrold R. Turner, Chicago IL, USA
2008 - 2010	Günzel, Fromm	DFG Research Grant (GU 447/11-1) "Barrier and channel properties of claudins in the renal diluting segment and distal nephron"
2006 - 2009	Fromm	Coordinator: DFG Research Unit 721 (FOR 721/1) "Molecular structure and function of the tight junction"
2006 - 2009	Amasheh, Fromm	Project 1 "Characterization of tight junction proteins as barrier or channel formers", in: DFG Research Unit 721 (FOR 721/1, TP 1) "Molecular structure and function of the tight junction"
2006 - 2009	Fromm, Schulzke	Project Z "Freeze fracture electron microscopy; general duties", in: DFG Research Unit 721 (FOR 721/1, TP Z) "Molecular structure and function of the tight junction"