|
"Physiology" we define by a central question: "How does it work?" For answering this question we apply several methods including molecular biology, electrophysiology, microbiology, biophysics, laser-scanning microscopy, and freeze-fracture electron microscopy We investigate all levels of the organism: molecules, cells, tissues, organs, and the whole body Our approach is translational as it combines basic research with topics related to diseases of the intestines, kidneys, nerves, and skin Main research topics are the tight junction and membrane channel molecules of the "intelligent borders of the body", the epithelia We perform numerous collaborative projects with colleagues from clinical departments Clinical Physiology / Nutritional Medicine is a unit within the Dept. of Gastroenterology, Rheumatology, and Infectious Diseases, located on the Campus Benjamin Franklin |
News update
Blog archive Hartmannsberger B, Ben-Kraiem A, Kramer S, Guidolin C, Kazerani I, Doppler K, Thomas D, Gurke R, Sisignano M, Kalelkar PP, García AJ, Monje PV, Sammeth M, Nusrat A, Brack A, Krug SM, Sommer C, Rittner HL (2024) TAM receptors mediate the Fpr2-driven pain resolution and fibrinolysis after nerve injury. Acta Neuropathol. (°IF 9.3) (accepted 05.12.2024, preprint BioRxiv) Krug SM, Fromm M (2024) Special Issue on "The tight junction and its proteins: From structure to pathologies". Int. J. Mol. Sci. 25(23): 13154 (3 pages), doi: 10.3390/ijms252313154 (°IF 4.9) (Editorial) Nagarajan SK, Weber J, Roderer D, Piontek J (2024) C. perfringens enterotoxin-claudin pore complex: Models for structure, mechanism of pore assembly and cation permeability. Comp. Struct. Biotechnol. J. (In press), doi: 10.1016/j.csbj.2024.11.048 (°IF 4.5) Marinovic I, Bartosova M, Levai E, Herzog R, Saleem A, Du Z, Zhang C, Sacnun JM, Pitaraki E, Sinis S, Ivan D, Krunic D, Lajqi T, Al Saeedi M, Szabo JA, Hausmann M, Domonkos P, Kratochwill K, Krug SM, Zarogiannis SG, Schmitt CP (2024) Molecular and functional characterization of the peritoneal mesothelium, a barrier for solute transport. Function (°IF 5.1) (accepted 25.11.2024)Mathew-Schmitt S, Oerter S, Reitenbach E, Gätzner S, Höchner A, Jahnke HG, Piontek J, Neuhaus W, Brachner A, Metzger M, Appelt-Menzel A (2024) Generation of advanced blood-brain barrier spheroids using human induced pluripotent stem cell-derived brain capillary endothelial-like cells. Adv. Biol. (°IF 3.2) (accepted 18.11.2024) Liebing E*, Krug SM* (*shared first authorship), Neurath MF, Siegmund B, Becker C (2024) Wall of resilience: How the intestinal epithelium prevents inflammatory onslaught in the gut. Cell. Mol. Gastroenterol. Hepatol. doi: 10.1016/j.jcmgh.2024.101423 (°IF 7.1) (Review, in press)van der Veen RE, Piontek J, Bieck M, Saiti A, Gonschior H, Lehmann M (2024) Claudin-4 polymerizes after a small extracellular claudin-3-like substitution. J. Biol. Chem. 300(10): 107693 (14 pages). doi: 10.1016/j.jbc.2024.107693 (°IF 4.0) Heimesaat MM, Mousavi S, Lobo de Sá FD, Peh E, Schulzke JD, Bücker R, Kittler S, Bereswill S (2024) Oral curcumin ameliorates acute murine campylobacteriosis. |
|
||
The Institute of Clinical Physiology was founded in 1969 and chaired until 1995 by
Klaus Hierholzer († 2007), followed by
Michael Wiederholt. (1995-2002) and
Michael Fromm
(2002-2014, now appointed as Charité seniorprofessor). Retired professors are Ulrich Hegel and Hans Ebel. Present head of Clinical Physiology / Nutritional Medicine is Jörg D.Schulzke. |
||
Address |
||
The main building of the
Campus Benjamin Franklin (CBF) of the Charité - Universitätsmedizin Berlin |
pics | |
Address: | Clinical Physiology / Nutritional Medicine Charité - Universitäsmedizin Berlin Campus Benjamin Franklin Hindenburgdamm 30 12203 Berlin (Steglitz), Germany |
|
Google Maps | ||
Public transportation: | Subway (U-Bahn "U9") or local train (S-Bahn "S1") to "Rathaus Steglitz", then change for bus 285 or M85, exit bus stop "Universitätsklinikum Benjamin Franklin" Local map Fares: Single ticket for 2 hrs, unlimited changes: "AB" 2.80 Euro or, ONLY bus 285 or M85 from Rathaus Steglitz: "Kurzstrecke" 1.70 Euro |
|
Head: |
Professor Dr. med. Jörg D. Schulzke joerg.schulzke@charite.de |
|
Phone: | +49 30 450-514531 | |
FAX: | +49 30 450-514962 | |
Representative of the German Research Foundation |
Hints and advice |